Natdecita 50mg injection contains the active substance decitabine. It is an antineoplastic drug that belongs to the class of medications called DNA methylation inhibitors. It is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and do not produce enough healthy blood cells). It is also used to treat a type of cancer called acute myeloid leukemia (AML). It works by stopping the cancer cells from growing.
Do not take this injection if you are allergic to Natdecita 50mg injection or any other ingredients of this medicine. Inform your physician if you have an infection, decreased blood cell count, liver disease, kidney disorder, and a heart disorder. This medicine is not recommended for children or young people below 18 years of age. This medicine can cause a serious immune reaction called differentiation syndrome. Report to your physician if you face any symptoms of sudden difficulty in breathing, cough, fever, or swelling in the body.
Natdecita 50mg injection should not be used in pregnant and breastfeeding women. Inform your physician if you are pregnant or breastfeeding. Use effective contraception throughout the therapy to avoid pregnancy. The common adverse reactions are decreased white blood cells, red blood cells, platelet counts, and increased body temperature.
Uses of Natdecita 50mg Injection
- Myelodysplastic syndromes (MDS)
- Acute myeloid leukemia (AML)
Therapeutic Effects of Natdecita 50mg Injection
Natdecita 50mg injection promotes hypomethylation of DNA and cellular differentiation or cell death after phosphorylation, direct incorporation into DNA, and inhibition of DNA methyltransferase. It works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.
Interaction of Natdecita 50mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Natdecita 50mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Natdecita 50mg Injection
- Do not store it above 25°C
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.