MITOTAX 300MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. MITOTAX 300MG INJECTION is used to treat ovarian and breast cancer as a first line of therapy and as a second line of treatment when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to treat the disease in affected individuals.
MITOTAX 300MG INJECTION is also used to treat advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to treat AIDS-related Kaposi’s sarcoma when other treatments (such as anthracyclines) are insufficient to treat the disease in affected individuals.
MITOTAX 300MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease.
Before receiving MITOTAX 300MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias).
MITOTAX 300MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving MITOTAX 300MG INJECTION which should be continued for next-6 months after completing the treatment. The medicine is also not recommended for use in breastfeeding women.
MITOTAX 300MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of receiving MITOTAX 300MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen.
USES OF MITOTAX 300MG INJECTION
- Treats ovarian and breast cancer.
- Treats advanced NSCLC (non-small cell lung cancer)
- Treats AIDS-related Kaposi’s sarcoma in affected individuals.
HOW MITOTAX 300MG INJECTION WORKS
MITOTAX 300MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and preventing its spread in affected individuals.
DIRECTIONS FOR USE
MITOTAX 300MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF MITOTAX 300MG INJECTION
COMMON
- minor allergic reactions such as flushing, rash and/or itching
- infections such as upper respiratory infection, urinary tract infection
- shortness of breath
- sore throat/mouth ulcers, sore and red mouth
- diarrhea, nausea, vomiting
- loss of hair
- pain in the muscles, cramps, joints
- fever, severe chills, headache, dizziness, tiredness, looking pale
- bleeding, bruising more easily than normal
- signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs
- temporary mild nail change and skin changes
- reactions at injection sites such as localized swelling, pain and/or redness of the skin.
UNCOMMON
- septic shock (severe drop in blood pressure) due to infections
- racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block
- fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat
- back pain, chest pain, pain around hands and feet, chills, abdominal pain.
RARE
- febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection
- motor neuropathy (disease that affects your body’s motor nerves)
- pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest)
- bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis)
- skin redness
- peritonitis (inflammation of abdominal layer)
- fever, dehydration, weakness
- anaphylactic reactions (life threatening allergic reaction).
HOW TO MANAGE SIDE EFFECTS
Diarrhea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.
Nausea and vomiting:
Try to receive MITOTAX 300MG INJECTION with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.
Headache:
If MITOTAX 300MG INJECTION causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of receiving MITOTAX 300MG INJECTION. If it lasts more than a week or severe, inform your doctor.
Dizziness:
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Tiredness:
Make sure you take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to receive MITOTAX 300MG INJECTION at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.