
G NIB 250 TABLET contains Gefitinib which belongs to the group of medicines called Antineoplastics. It is indicated in adults for the management of locally advanced or metastatic non-small cell lung cancer (NSCLC) who have activating mutation of the EGFR-TK.
It is generally characterized by symptoms such as chest pain or discomfort, persistent cough, trouble breathing, wheezing, tiredness and difficulty while swallowing which may be diagnosed as any of its type as adenocarcinoma (cancer involving the outer part of the lung), squamous cell carcinoma (cancer occurring in the centre part of the lungs) and large cell carcinoma (cancer that can occur in any part of the lung).
Along with this management, your doctor might ask you to take liver function test to assess your liver function.
G NIB 250 TABLET is not recommended for use in patients who are allergic to Gefitinib. Before taking G NIB 250 TABLET, inform your doctor if you have other lung problems, liver or kidney problems.
G NIB 250 TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking G NIB 250 TABLET.
The most common side effects of taking G NIB 250 TABLET are diarrhoea, vomiting, nausea, skin reactions, loss of appetite, weakness and red or sore mouth. Consult with your doctor if any of the symptoms worsen.
USES OF G NIB 250 TABLET
- Used to manage adults with non-small cell lung cancer
HOW G NIB 250 TABLET WORKS
G NIB 250 TABLET works by decreasing the survival rate and proliferation of malignant cancer cells in lung tissues by blocking a protein called epidermal growth factor receptor (EGFR) which is responsible for the growth and spread of cancer cell thereby controlling the growth and spread of cancer cells to other parts of the body.
DIRECTIONS FOR USE
Take G NIB 250 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of G NIB 250 TABLET for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF G NIB 250 TABLET
COMMON
- diarrhoea
- vomiting
- nausea
- skin reactions (acne-like rash)
- loss of appetite
- weakness
- red or sore and dry mouth
- dry, red or itchy eyes
- red and sore eyelids
- nail problems
- hair loss
- fever
- bleeding such as nosebleed or blood in urine
- signs of cystitis such as burning sensations while urinating, urgent need to urinate
UNCOMMON
- signs of inflamed pancreas such as very severe pain in the upper part of the abdomen, severe nausea and vomiting
- signs of inflammation of the liver such as general feeling of being unwell, with or without possible jaundice (yellowing of the skin and eyes)
- signs of gastrointestinal perforation such as severe stomach pain, chills, fever
- signs of palmar-plantar erythrodysaesthesia syndrome or hand and foot syndrome such as skin reaction on the palms of the hands and soles of the feet with tingling, numbness, swelling, redness or pain
RARE
- signs of inflammation of the blood vessels in the skin such as bruising or patches of non-blanching rash on the skin
- signs of haemorrhagic cystitis (inflammatory condition of urinary bladder) such as burning sensation while urinating, urgent need to urinate along with blood in the urine
Stop taking G NIB 250 TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reaction such as swollen face, lips, tongue or throat, red and itchy skin, nettle rash and difficulty breathing and difficulty in swallowing
- signs of interstitial lung disease (inflammation and scarring of lung disease) such as serious breathlessness, or sudden worsening of breathlessness possibly with a cough or fever
- dehydration due to long term or severe diarrhoea, vomiting, nausea, or loss of appetite
- signs of an ulcer on the surface of the eye (cornea) such as pain, redness, watery eyes, light sensitivity, changes in vision or ingrowing eyelashes