Pexitaz 500mg injection is an anticancer medicine containing the active ingredient Pemetrexed. It belongs to the medication class known as an antifolate agent. It is used to treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This medicine is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects.
Blood tests will be taken before each infusion to determine whether your kidney and liver functions are adequate and whether you have enough blood cells to receive this medicine. Before starting treatment with Pexitaz 500mg injection, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems, heart disorders, or fluid accumulation in the lungs. Report to your doctor if you recently had or currently having radiotherapy or any vaccination before taking this medication.
Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and at least six months after the last dose of Pexitaz 500mg injection. In men, it is recommended not to father a child during and up to 3 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age.
Uses of Pexitaz 500mg Injection
- Malignant pleural mesothelioma
- Non-small cell lung carcinoma
Therapeutic Effects of Pexitaz 500mg Injection
Pexitaz 500mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.
Interaction of Pexitaz 500mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as may interact with Pexitaz 500mg and reduce effectiveness by causing undesirable side effects.
More Information about Pexitaz 500mg Injection
- Keep the tablets away from light and moisture.
- Store refrigerated at 2°C to 8°C.
- Keep the tablets out of the reach of children and animals.
How to consume Pexitaz 500mg Injection
Pexitaz 500mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices for Pexitaz 500mg Injection
Pregnancy
Do not take Pexitaz 500mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.
Breast Feeding
It is unsafe to breastfeed while taking Pexitaz 500mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.
Lungs
Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking Pexitaz 500mg.
Liver
Inform your physician about any underlying liver disorders before taking Pexitaz 500mg, as this medication should be used with caution in liver disease patients.
Alcohol
It is unknown whether consuming alcohol while taking a Pexitaz 500mg injection is safe. Please speak with your physician.
Driving
While taking Pexitaz 500mg, driving or using machines is unsafe because it may cause nausea, fatigue, vomiting, etc. Talk to your doctor for more information.