Globucel 10gm Injection 100ml is an immunostimulant drug in the category of immunoglobulin derivatives, containing the active ingredient Human Normal Immunoglobulin. It is used as a replacement therapy for individuals with primary immunodeficiency disorders (PIDs), where the body's immune system cannot produce sufficient antibodies to fight off infections. The medication is also used to modulate or regulate the immune system in certain autoimmune and inflammatory conditions. It can help reduce excessive inflammation and suppress abnormal immune responses.
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. If you have a selective IgA deficiency, there is a risk of developing antibodies against IgA. In such cases, normal human immunoglobulin should be used cautiously or avoided altogether. Inform your physician if you have a history of IgA deficiency. After receiving Globucel 10gm Injection 100ml, it is possible to experience a temporary decrease in the concentration of white blood cells, a condition named as neutropenia (low neutrophil count) which resolves spontaneously within a week.
The administration of normal human immunoglobulin may interfere with the effectiveness of live attenuated vaccines. It is advisable to avoid live vaccines for a certain period after receiving this drug. The overdose of Globucel 10gm Injection 100ml may lead to fluid overload, particularly in patients with pre-existing heart failure or compromised renal function. Patients with such conditions should be carefully monitored during infusion. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. The use of this medicine during pregnancy or breastfeeding should be discussed with your physician.